New Research From Return Path Shows Sender Reputation and Email Deliverability Are Tightly LinkedEmail data solutions provider Return Path released its 2019 Sender Score Benchmark. Using comprehensive data from Sender Score and Return Path’s Reputation Network, this annual report provides expert analysis and insights on how reputation impacts inbox placement for commercial email senders.“Sender reputation offers unique insight into the source of each email, making it a key factor in those filtering decisions.”Based on analysis of more than 4 trillion email messages, The 2019 Sender Score Benchmark reveals that highly reputable email marketers are far more likely to reach their intended audience than peers with lower reputation scores. For example, senders scoring 91-100 (the best possible reputation score) had 91 percent of their messages delivered. This figure drops to 71 percent for senders scoring 81-90, and 44 percent for senders scoring 71-80.“Email remains the marketer’s go-to channel. But if email doesn’t reach the inbox, brands lose the opportunity to connect with customers and ultimately make a sale—so every message counts,” said Tom Sather, senior director of research at Return Path. “Since the initial Sender Score Benchmark Report in 2012, our research has consistently shown a clear link between reputation and deliverability. That’s why monitoring your reputation and maintaining it at the highest level possible is critical to email marketing success.”Marketing Technology News: PepsiCo Foodservice Unveils New Digital Lab to Help Restaurants Thrive In The Evolving Digital MarketplaceSpam complaints are one important factor used by mailbox providers in determining which messages are unwanted and should be filtered to the junk folder. Not surprisingly, there is also a strong correlation between spam complaints and sender reputation. While year-over-year spam complaints were higher across the board, senders scoring 91-100 had an average complaint rate of just 0.9 percent. For senders scoring 81-90, this metric jumped to 4.7 percent—more than five times higher than the best senders.“Mailbox providers face competition just like any other business, so they are constantly improving their filtering algorithms to create a better inbox experience for their users,” continued Sather. “Sender reputation offers unique insight into the source of each email, making it a key factor in those filtering decisions.”Marketing Technology News: Motionloft named a 2019 Gartner “Cool Vendor” in Location Services and ApplicationsThe overall quality of email has increased dramatically since Return Path’s first Sender Score Benchmark Report. In 2012, that report found that 60 percent of all email was sent by the least reputable senders—those with a Sender Score of 10 or less—while the best senders accounted for just six percent of total volume. Today, 42 percent of email comes from top senders, while email from the least reputable senders is down to just 16 percent. This shift can be attributed to the evolution of filtering technology and an increased focus on sender reputation at the mailbox provider level, all of which has made it more difficult—and far less profitable—for spammers to deliver their messages.Marketing Technology News: Verasity Announces Integration with YouTube For Highly Reputable Senders, 91 Percent of Emails Reach Their Intended Audience—Compared to 70 Percent or Less for All Other Senders PRNewswireMay 23, 2019, 5:09 pmMay 23, 2019 Email Data SolutionsMarketing TechnologyNewsReputation Networkreturn pathSender ScoreSender Score Benchmark Previous ArticleMediafly Unveils New Sales Enablement Platform Experience for the Future of Evolved SellingNext ArticleSurvey: 96% of Enterprises Encounter Training Data Quality and Labeling Challenges in Machine Learning Projects
Tell us about your role and the team/technology you handle at Verto Analytics.I am our Head of Custom Research, responsible for delivering high-quality data and insights to our clients, some of which like Google are among the biggest technology companies in the world. I am responsible for using our data assets, methodology, panels, to create insights and research to answer our customers’ business questions.Why are B2B marketing teams steadily moving toward Applied Data Science for Sales and Marketing initiatives?Traditionally this used to be very F2F-driven, all about relationships and real people talking to each other. However, in today’s digital world an increasing share of B2B decisions and investments are done online which leads to the marketing and sales focus to also pivot to micro-targeting using online clickstream data to understand who is a possible consumer thereby making marketing spend more efficient and targeted. In order to accomplish this, Data Science and Engineering are key to synthesize that information from large volumes of data. For example what actions/pathing indicate that someone is in-market for a B2B product?What is the current definition of Mobile Customer Experience? How is it different from desktop CX?We define mobile customer experience to be the result of the user’s activities and engagement, interaction and its smoothness, with mobile devices and digital services through these devices, as opposed to the use of similar assets but on the big screen computer-type devices. Increasingly there is a shift of online purchasing and decision making to Mobile devices as User Experiences on these devices are becoming more efficient and seamless.Tell us more about the changing nature of Digital Experiences and how it impacts experience delivered through the Mobile Marketing campaigns?Today’s digital campaigns, and definitely the capabilities brought on by mobile, are enormous. The biggest differences are in the fact that one can reach the individual consumer, on a one-by-one basis (mobile devices are not shared), all the time and everywhere, at the point of context and user attention – using for example locations and other such contextual variables based on online clickstream data are integrated parts of the campaign delivery and targeting.How have the customer’s expectations evolved in the last 2-3 years when it comes to interacting with brands over Mobile devices? Do you have some specific data related to this evolution of customer preference?The expectations of customers have changed significantly. Back in the day, it was thought that mobiles are yet another screen or device to use in targeting people. Today’s brands expect more native and sophisticated use of the unique characteristics of mobile devices (see above), and increasingly want to make sure the role of mobile advertising in the overall mix is well thought and optimized.We have data to quantify this as well given the longitudinal nature of the panel and can compare if panelists are more/less active on their Mobile devices compared to a year or more ago.Tell us about the three major takeaways from your recent report on Mobile data. How can marketing team better leverage your report findings to understand consumer behavior?The report’s major takeways are less actionable than they are predictive of several key possible changes in mobile.Consumer Attention at Unlock Will Become “a Thing”: The report begins to peel back and inspect the first moments of consumer attention on mobile. The findings certainly support that those first moments done right positively impact companies, influencing engagement, content consumption and revenues. So we think that this topic will get greater attention from brands, publishers, ad tech, carriers, smartphone OEMs and more.Research Must Continue to Evolve: The findings create as many questions as they answer. Given the potential impact on so many mobile stakeholders, we certainly expect this to be the first, but not the last, set of insights on this topic.Smartphones Will Change: What is certainly clear, is that our findings support that our “smart”phones could, would and ultimately will be smarter when they do a better job of more frictionlessly delivering the content and apps a consumer may want to use. There are many ways this might be done. Many will be tried, and Verto looks forward to trying to understand how well they work.How do you see Big Data and Customer Intelligence coming together to solve identity-related issues?We believe the fact that we have opt-in based datasets and services, and aggregators and intermediaries like Liveramp which make it possible to do data deals and overlaps, with anonymous matching, respecting all the local laws.Tell us about the various steps of the AI-powered Mobile Marketing journeys. How do consumers from different global locations interact with advertisements and marketing campaigns?There are lots of differences how different cultures react to contextual and more intelligent advertising. For example, Europeans tend to be more conservative with privacy, while Asians and Americans are more receptive to intelligent and contextual targeting.What are the different scenarios AI could be applied to in Marketing, Sales and Customer Service?There are many. We see that continuous optimization and on-the-fly adjustment of campaign creatives and targeting is one area where more intelligent use of return-path data and feedback loops could pose a big opportunity for AI (no static campaigns), the big opportunity is to provide real-time support via bots, which we have seen increasing in use lately.How do you build analytics around Cloud and Enterprise Mobility platforms?We are very customer-driven, so we have work flows and teams who understand and talk with customers about their needs, and we have our HQ-driven development tracks in which they implement these features into our cloud-based platform – productizing the solutions so that they are available to a high number of customers.Tell us about your customer experience products. How can MarTech customers benefit from your AI/ML products at Verto Analytics?Our single source approach (telemetry data on both PC and Mobile for the same user and ability to survey those users) enables us to get in-depth information into the consumer mindset and actions.We start with business questions, and using our methodology my team and I would propose customized solutions using both telemetry and attitudinal data to address our clients’ business problems.What is the current state of machine learning and AI for digital transformation?There appears to be a lot of hype but it’s unclear how effective the results are. Technologies and algorithms are there, but we still need to make sure the data that goes as an input is of high quality, and there is transparency and better ROI measurement especially on the ad targeting/segmentation front.How much of this state is influenced by the maturity of Data Science and Machine Learning algorithms?The algorithms and tools themselves are mature however as mentioned above the output/quality is dependent on what goes in. For example, a lot of players claim to be able to do advanced targeting using look alike modelling but is the input of the best quality? Is the output being effectively measured? Theses are questions business leaders need to consider beyond the maturity of Data Science Tools and algorithms.What are the major pain points for Data Analysts and Engineers in building/ scaling Analytics for relevant customer experience?It is always the extent of customization. Companies like us are interested in solving problems, but for us to do our work well and maximize the value-added, we need to be able to map similar problems across many customers so that we can scale our solutions more effectively.How do you work with AI/ Machine Learning at Verto Analytics?We have people with strong skillsets in this area, and apply machine learning in projects and use cases whenever it makes sense – not because it is a “cool thing to do”. For example, segmentation and clustering similar users is a common use case. About Verto Analytics About VinayakAbout Verto AnalyticsAbout Vinayak Vinayak Nair is the VP of Custom Analytics at Verto Analytics and currently works with Media, Tech, and Market Research companies to help synthesize digital consumer behavior utilizing a proprietary single-source, multi-platform panel. Prior to joining Verto Analytics, he was the Director of Analytics at comScore where he helped build and launch Audience Measurement products. TechBytes with Vinayak Nair, VP Research Ops and Custom Analytics at Verto Analytics Sudipto GhoshMay 29, 2019, 2:30 pmMay 29, 2019 Verto Analytics is a media measurement company that offers a holistic view of the consumer—their behavior along with demographics, lifestyles, attitudes, and interests.Verto owns and operates single-source, passively metered consumer panels in select markets that gives it the power to measure behavioral changes over time across all media—second by second. Brands, publishers, and researchers can benchmark against competitors and the market, fill in the gaps in the consumer journey, and identify ways to increase engagement and loyalty, with Verto’s services. B2Bclickstream datadata analyticsData and Insightsdata scienceTechBytesVerto AnalyticsVinayak Nair Previous ArticleOpenText Named a Customer Communications Management Leader in 2019 Aspire CCM LeaderboardNext ArticleThe Secret Life of an Events Optimiser
Source: https://www.nature.com/articles/s41586-018-0692-z Aedes aegypti mosquito on human skin. Image Credit: khlungcenter / Shutterstock By Dr. Ananya Mandal, MDNov 25 2018A new study has tried to assess the genetic variants among mosquitoes that make them more susceptible to spreading deadly viral diseases such as dengue, yellow fever, Zika and chikungunya and more resistant to insecticides that are used to kill them.The study titled, ‘Improved reference genome of Aedes aegypti informs arbovirus vector control’, by researchers from seven countries, including Australia’s QIMR Berghofer Medical Research Institute, has mapped the genetic make-up of these insects which could be ground breaking in vector control. The team was looking at the genomes of Aedes aegypti mosquitoes that carry viruses like Zika and dengue. They noted that some newly discovered genes could make them resistant to insecticides.Modification of these resistant genes may help stop the mosquitoes from spreading disease, the researchers hope. Dr. Gordana Rasic, one of the researchers said, “One of the key things that we want to achieve is to modify these mosquitoes in a way that will help control them.” They looked at “physical and cytogenetic maps of the mosquitoes to see how these mosquitoes differed in their preference for human hosts for biting as well as how it alters their egg laying sites. They noted that there is a specific locus called the M locus on the mosquito genome where there is a variation in the glutathione S-transferase genes or the GST gene that is important for resistance to insecticides.Related StoriesDoes genetic testing affect psychosocial health?Gene modulation goes wireless hacking the “boss gene”Study: Causes of anorexia are likely metabolic and psychologicalThese GST genes are actually responsible for coding for proteins that detoxify and excrete the insecticides that are used to kill the mosquitoes. When modified these GST genes help the mosquitoes develop a resistance to the insecticides used against them and this makes the chemical ineffective against the pests.A look at these genes of the AaegL5 genome would help interventional strategies for vector control in controlling mosquitoes that carry the dengue virus and the Zika virus.The authors write, “high-quality genome assembly and annotation described here will enable major advances in mosquito biology.”The team also found variants of “chemosensory ionotropic receptors” among the mosquitoes. These connect the attraction of the mosquitoes to certain smells and tastes present on human skin that make them more prone to mosquito bites.The authors state in their work that this could provide clues to developing “novel mosquito repellents. ‘Sterile Insect Technique’ and ‘Incompatible Insect Technique’” that could help reduce mosquito populations. Genetic modification of the male mosquitoes could help alter the genes of the progeny is ways so that they fail to transmit the infection.The authors sign off that better understanding of the genetics of mosquitoes could “facilitate genetic control of mosquitoes that infect many hundreds of millions of people with arboviruses every year.”Mosquito bites are known to spread several life-threatening diseases including malaria, dengue, chikungunya, zika etc.Zika alone affects around 86 countries and regions around the world and can affect pregnant mothers and severely harm the unborn babies.Dengue too is a viral infection carried by mosquitoes that causes deadly hemorrhagic fever or fever along with very low platelet counts that can cause spontaneous bleeding.Malaria is a parasitic infection that still manages to kill hundreds of thousands around the world.
Source:https://www.ucr.edu/ Reviewed by James Ives, M.Psych. (Editor)Feb 6 2019Astronomers at the University of California, Riverside, have teamed with teachers at the California School for the Deaf, Riverside, or CSDR, to design an astronomy workshop for students with hearing loss that can be easily used in classrooms, museums, fairs, and other public events.The workshop utilized a sound stage that allowed the CSDR students to “feel” vibrations from rockets, stars, galaxies, supernovae, and even remnants of the Big Bang itself. The members of the team have made their materials public and written up their experiences to help teachers and other educators worldwide to similarly engage the deaf community in STEM activities.Since 2015, Gillian Wilson, senior associate vice chancellor for research and economic development and a professor of physics and astronomy at UCR, and Mario De Leo-Winkler, director of the National System of Researchers of Mexico and a former postdoctoral scholar at UCR, have developed astronomy outreach activities – astronomy photography competitions, traveling astronomy exhibitions, K12 workshops, interdisciplinary honors thesis projects, hands-on undergraduate astrophotography – that have touched 40,000 people.They have worked closely with CSDR teachers before, ensuring American Sign Language, or ASL, at public astronomy events, but had never developed an activity targeted for the deaf community.Around 360 million people worldwide suffer from hearing loss. In the United States, about 11 million citizens are functionally deaf or report some trouble hearing. The city of Riverside contains a large concentration of deaf students because it is home to CSDR, the only public school for the deaf in Southern California.”Designers of informal STEM education and public outreach activities often overlook people with hearing loss,” De Leo-Winkler said. “For our workshop we decided to focus on astronomy -a gateway to science- because of the breathtaking imagery it offers, the big questions it tackles, and its increasingly interdisciplinary nature. We used storytelling, videos, and images in the workshop to bring meaning to the sounds of the universe — all of which made for a very engaging experience for the students.”Related StoriesTAU’s new Translational Medical Research Center acquires MILabs’ VECTor PET/SPECT/CTMalaria drug may help those with hereditary hearing loss finds studySmarter, more educated people get a cognitive ‘head start’, but aren’t protected from Alzheimer’s”The students clearly loved the experience,” said Wilson, “and that’s the whole point.”De Leo-Winkler and Wilson presented the workshop multiple times over three days at CSDR, using feedback from the teachers and students not only to better convey the scientific concepts, but also to improve the students’ experience. Their presentation took the students on a cosmic voyage: the students “traveled” from Earth, where thunderstorms were raging, to the sun, where they experienced a solar storm. The voyage continued to Jupiter, flew through the rings of Saturn, and continued on to stars Alpha Centauri A and B. The students flew past the Large Magellanic Cloud galaxy and encountered a supernovae explosion. The voyage ended by encountering the Cosmic Microwave Background, the radiation leftover from the Big Bang. Temperature variations in this radiation were sonified to allow the students to experience them as vibrations.”Deaf individuals have a more developed sense of touch than hearing people due to their brain ‘rewiring’ in a process called neuroplasticity,” De Leo-Winkler said. “We paid close attention to this when designing the workshop. The students sit on a special interlocking wooden floor and face a TV screen. When sounds are played, they are transmitted by the sound system onto the floorboard as vibrations. Meanwhile videos and images that provide information are displayed on the screen. We tell the story and an interpreter signs what we say in American Sign Language.”The workshop opens a new way of communicating cosmic phenomena, related to sound, to the deaf community, and opens the door for further developments in public outreach using vibrations to engage and excite students.”It was very important to us to make our materials publicly accessible,” Wilson said. “There are dozens of these sound stages in the U.S. alone. Our workshop could easily be adapted to include other astronomical phenomena or to focus on another scientific discipline. I hope knowing that this was such a positive experience for us will inspire others.”
Source:https://www.esmo.org/ Reviewed by James Ives, M.Psych. (Editor)Feb 25 2019First study to investigate long-term effect of postoperative chemotherapy or radiotherapy on sperm count and concentrationMen with early stage testicular cancer can safely receive one course of chemotherapy or radiotherapy after surgery without it having a long-term effect on their sperm count, according to a study published in the leading cancer journal Annals of Oncology today (Monday).Although it is known already that several rounds of chemotherapy or high doses of radiotherapy given to men with more advanced testicular cancer can reduce sperm count and concentration, it has been unclear whether a single cycle of chemotherapy or radiotherapy would have a similar effect in men with stage I disease.Dr Kristina Weibring, a cancer doctor at the Karolinska University Hospital in Stockholm, Sweden, who led the study, said: “We wanted to examine in more detail if postoperative treatment, given to decrease the risk of recurrence after the removal of the tumorous testicle, would affect the sperm count and sperm concentration long term in testicular cancer patients with no spread of the disease. To our knowledge, no such study has been done before.”This is important to find out, since treatment with one course of postoperative chemotherapy has been shown to decrease the risk of relapse substantially, thereby reducing the number of patients having to be treated with several courses of chemotherapy.”Testicular cancer is the most common cancer in young men between the ages of 15 and 40. When it is diagnosed, all patients have the testicle containing the tumour removed, a surgical procedure called orchiectomy.In this study, 182 men aged between 18 and 50, diagnosed with stage I testicular cancer and who had had an orchiectomy within the past five years, took part in the study between 2001 and 2006. They were treated either in Stockholm or Lund. After surgery, they received radiotherapy (14 fractions of 1.8 Gy each, up to a total dose of 25 Gy) or one course of chemotherapy, or were managed by surveillance, meaning there was no postoperative treatment. They provided semen samples after orchiectomy but before further treatment, and then six months, one year, two years, three years and five years thereafter. From 2006 onwards, radiotherapy was no longer used as a standard treatment in Sweden because of the risk of causing secondary cancer.”We found no clinically significant detrimental long-term effect in either total sperm number or sperm concentration, irrespective of the type of postoperative treatment received,” said Dr Weibring. “Among men who received radiotherapy, there was a distinct decrease in average sperm number and concentration six months after treatment, though not in those who received chemotherapy. However, sperm number and concentration recovered in the radiotherapy group after six months, and continued to increase in all groups up to five years after treatment.Related StoriesResearchers use AI to develop early gastric cancer endoscopic diagnosis systemLiving with advanced breast cancerHow cell-free DNA can be targeted to prevent spread of tumors”I am very excited to see these results as I wasn’t expecting sperm to recover so well after postoperative treatment. I didn’t expect as negative an effect as if the patient had received many courses of chemotherapy, since it is much more toxic, but I was not sure how much the sperm would be affected by one course.”With the results of this study we can give the patients more adequate information on potential side effects from postoperative treatment. Testicular cancer patients are often young men wanting to father children at some point, and we find, in many cases, that the patients are afraid of the potential risk of infertility caused by chemotherapeutic treatment. These findings should provide some reassurance to them.”A well-known problem for men diagnosed with testicular cancer is an impaired ability to create sperm. A condition called testicular dysgenesis syndrome, characterised by poor semen quality among other things, may play a role in this and is also associated with a higher risk of developing testicular cancer. In addition, the orchiectomy and the cancer itself may also affect sperm quality. The removal of one testicle does not necessarily affect a man’s sperm count and concentration as the remaining testicle can compensate.Dr Weibring concluded: “Our results are promising but more studies are needed, and we still recommend sperm banking before orchiectomy as a number of patients may have low sperm counts at the time of diagnosis that persists after postoperative treatment. In addition, the type of testicular cancer and whether or not it will need further treatments are unknown factors before the orchiectomy. Assisted reproductive measures may be necessary for these patients regardless of any treatment given.”Editor-in-chief of Annals of Oncology, Professor Fabrice André, Professor in the Department of Medical Oncology, Institut Gustave Roussy, Villejuif, France, commented: “This study, together with other research efforts, explores the paths to recovering a normal life after cancer. The finding that one course of chemotherapy has minimal impact on sperm count offers hope for thousands of patients worldwide, but we all must keep in mind that these data are preliminary and will require validation before we can use them in clinics. The next step will be to establish how to predict the toxic effects on sperm count of different chemotherapy regimens.”
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